1.Write a paragraph on ESBL ( Extended spectrum betalactamase). Please address the following points.
Definition ( type of antibiotics for which the organism/s are resistant)
Bacteria carrying ESBL gene
The magnitude of the problem in the US ( disease and mortality)
Genetic mechanism ( Chromosomal vs plasmid mediated)
How the resistant gene is acquired ( mutation or specific horizontal gene transfer).
2. Write a one paragraph summary for each topic below with a particular focus on medical application of the method or tool.
Restriction enzyme
Polymerase Chain reaction (PCR)